limits of ball mill micron

effect of ball and feed particle size distribution on the milling efficiency of a ball mill: an attainable region approach - sciencedirect

effect of ball and feed particle size distribution on the milling efficiency of a ball mill: an attainable region approach - sciencedirect

In this article, alternative forms of optimizing the milling efficiency of a laboratory scale ball mill by varying the grinding media size distribution and the feed material particle size distribution were investigated. Silica ore was used as the test material. The experimental parameters that were kept constant in this investigation was the grinding media filling, powder filling and the mill rotational speed. The data obtained from these batch tests was then analyzed using a model free technique called the Attainable Region method. This analysis technique showed that the required product fineness is a function of grinding media and feed material size distributions. It was also observed from the experimental results that in order to increase the milling efficiency of a ball mill, towards optimum production of material in the desired size class, there is a need to correlate the ball size and the feed size distributions.

catalent micron technologies - catalent

catalent micron technologies - catalent

Catalent Micron Technologies is a leading international provider of particle size reduction and analytical services. We deliver first-class pharmaceutical contract micronization, milling and analytical services combining quality, speed-of-response and industry-leading expertise.

Catalent Micron Technologies has more than 25 years experience handling pharmaceutical materials and is a leader in air jet milling micronization. We are capable of processing both R&D and commercial volumes alike and are equipped with state-of-the-art systems to ensure total product containment and quality. We can provide tailored solutions for your molecule incorporating salt form optimization, pre-formulation services as well as formulation of your micronized materials into optimal inhaled or oral dose form through clinical and commercial supply.

Catalent Micron Technologies is the preferred solution provider for the most complex, specialized requirements in pharmaceutical micronization, we have the expertise to handle your toughest particle size specifications.

From API optimization, particle size optimization and formulation services, to drug delivery technology selection and final dose form design services; Catalent can help you at the earliest stages of the drug development process. Our team can provide end-to-end solutions to accelerate your programs to clinic and to market, utilizing our broadest expertise, best technologies and rigorous science, including:

Catalent Micron Technologies understands the challenges in technology transfer and lean manufacturing and will provide expertise in milling/micronization to assist our clients with their Quality by Design (QbD) initiatives. We develop screening and optimization Design of Experiment (DOE) protocols and conduct well-defined milling/micronization runs. We also provide insightful risk assessment to custom develop the optimal design space for our clients product. Our QbD offerings are part of a dedicated approach to customer support, to fuel continuous process improvements, cost savings, and regulatory flexibility.

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